{"product_id":"treat-pre-eclampsia-eclampsia-pre-eclampsia-magnesium-verla","title":"Treat pre eclampsia, eclampsia, pre-eclampsia, Magnesium Verla®","description":"\u003ch1 class=\"flex-1 break-words text-xl mobile:text-3xl\" data-qa-id=\"product-title\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eMagnesium Verla® iv 20mmol\/10ml\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cspan\u003eDosage form: \u003c\/span\u003e\u003cspan\u003eInfusion solution concentrate\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eUsed to treat pre eclampsia, eclampsia, preterm labor tendencies and severe magnesium deficiency\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003csection class=\"text-primary-max-dark\"\u003e\n\u003ch2 class=\"text-s font-bold\"\u003e\u003cspan\u003eactive Treat pre eclampsia, eclampsia, pre-eclampsia, Magnesium ingredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul class=\"mb-3.5 list-disc pl-5 text-s\"\u003e\n\u003cli\u003e\u003cspan\u003e4929.5 mg magnesium sulfate-7 water\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003csection class=\"text-primary-max-dark\"\u003e\n\u003ch3 class=\"text-s font-bold\"\u003e\u003cspan\u003eTreat pre eclampsia, eclampsia, pre-eclampsia, Magnesium ingredients\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul class=\"mb-3.5 list-disc pl-5 text-s\"\u003e\n\u003cli\u003e\u003cspan\u003ewater for injections\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSulfuric acid for pH adjustment\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"font-bold\"\u003e\n\u003cspan\u003eIndication Treat pre eclampsia, eclampsia, pre-eclampsia, Magnesium\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe drug is a mineral supplement.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn preeclampsia, eclampsia, tendencies towards premature birth, severe magnesium deficiency (normal values ​​of magnesium in the serum 0.8 - 1.1 mmol\/l).\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"font-bold\"\u003e\n\u003cspan\u003eDosage\u003cspan\u003e Treat pre eclampsia, eclampsia, pre-eclampsia, Magnesium\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAlways use the medicine exactly as described or as your doctor or pharmacist has told you.\u003cspan\u003e \u003c\/span\u003eAsk your doctor or pharmacist if you are not sure.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe dosage depends on the indication and on the magnesium serum level.\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eThe recommended dosage is\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eFor preeclampsia, eclampsia: 4 - 6 g magnesium sulfate (16 - 24 mmol magnesium) iv in diluted form using a perfusor or short infusion over 15 - 20 minutes.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMaintenance dose 1 - 2 g magnesium sulfate \/ hour (4 - 8 mmol magnesium \/ hour) up to 24 - 48 hours postpartum.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you are trying to give birth early, as an additional therapy to tocolysis with betamimetics: 4 - 8 mmol magnesium \/ hour.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor severe magnesium deficiency: 20 mmol magnesium \/ day.\u003c\/span\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you use more than you should:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe main symptoms and general signs of overdose are muscle weakness, disappearance of deep tendon reflexes, drop in blood pressure and heart rate, increase in skin blood flow, ECG changes, vomiting, sedation and confusion.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf the plasma magnesium concentration exceeds 2 mmol\/l, the deep tendon reflexes are weakened, at around 5 mmol\/l they are no longer present and respiratory depression occurs.\u003cspan\u003e \u003c\/span\u003eComa occurs at 6.0 - 7.5 mmol\/l and respiratory paralysis and diastolic cardiac arrest from 8 mmol\/l.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMagnesium intoxication should be treated with intravenous calcium supply - as an antidote - (e.g. slow iv administration of 10 ml of a 10% calcium gluconate solution).\u003cspan\u003e \u003c\/span\u003eIn addition, the cholinesterase blocker neostigmine should be administered because it increases acetylcholine concentration and antagonizes the muscle relaxant effect of magnesium.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you forgot the application\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eDo not apply twice if you forget the previous application.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 class=\"font-bold\"\u003e\n\u003cspan\u003eway Treat pre eclampsia, eclampsia, pre-eclampsia, Magnesium\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe concentrate for infusion should be diluted and then infused intravenously.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSuitable dilution solutions are e.g.\u003cspan\u003e \u003c\/span\u003eB.: 5% glucose and 0.9% sodium chloride solution.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAs an adjunctive therapy to tocolysis with betamimetics, 0.9% sodium chloride solution should be used as a dilution solution instead of the 5% glucose solution because of the hyperglycaemic effect of the tocolytics.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe ready-to-use solution for infusion should be used immediately after dilution.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBecause of possible precipitation, parenteral magnesium sulphate administrations should not be mixed with solutions containing calcium, phosphate, tetracycline or alcohol.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eIn attempts to give birth prematurely, as adjunctive therapy to tocolysis with betamimetics:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eTo prepare the infusion solution z.\u003cspan\u003e \u003c\/span\u003eB. Mix 2 ampoules with 480 ml diluent.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor severe magnesium deficiency:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eTo prepare the infusion solution z.\u003cspan\u003e \u003c\/span\u003eB. Mix 1 ampoule with 990 ml dilution solution.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe dosage depends on the area of ​​application or the magnesium serum level.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch5 class=\"font-bold\"\u003e\n\u003cspan\u003eSide effects\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h5\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLike all medicines, this medicine can cause side effects, although not everybody gets them.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWhen given intravenously, there is generally a meaningless feeling of warmth and flushing (reddening of the skin).\u003cspan\u003e \u003c\/span\u003eIf magnesium sulfate is administered parenterally too quickly, temporary side effects in the form of nausea, headaches, tingling, sweating, agitation, restlessness, drowsiness and slowing of heart and breathing activity may occur, particularly in vasolatile patients.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn addition, parenteral administration of magnesium can lead to bradycardia, conduction disorders and peripheral vasodilatation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDose reduction or discontinuation of the preparation generally lead to a rapid disappearance of these side effects.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you get any side effects, talk to your doctor or pharmacist.\u003cspan\u003e \u003c\/span\u003eThis also applies to side effects that are not specified.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"font-bold\"\u003e\n\u003cspan\u003eInteractions Treat pre eclampsia, eclampsia, pre-eclampsia, Magnesium\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eUse with other medicines:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eTell your doctor or pharmacist if you are using, have recently used or might use any other medicines.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDiuretics, aminoglycoside antibiotics (such as gentamycin, tobramycin, amphotericin B), immunosuppressants (such as cyclosporine A), cytostatics (such as cisplatin), and digitalis glycosides cause increased excretion of magnesium through the kidneys.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe following drugs should not be given at the same time:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eCurare-type muscle relaxants - these enhance the action of magnesium at the motor endplate;\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBarbiturates, narcotics, or other hypnotics - these increase the risk of respiratory depression;\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCalcium salts - these reduce the effects of magnesium.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe simultaneous administration of magnesium and calcium antagonists may only take place under intensive care conditions, as it can lead to an increase in the blood pressure-lowering effects.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch5 class=\"font-bold\"\u003e\n\u003cspan\u003eContraindications\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h5\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eThe drug must not be used\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eif you are allergic to magnesium sulfate or any of the other ingredients of this medicine.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ewith pronounced bradycardia (slow heart activity),\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ein myasthenia gravis (muscle weakness)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ewith AV block (interruption of the conduction system in the heart)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ewith a tendency to infection stones (calcium magnesium ammonium phosphate stones).\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch5 class=\"font-bold\"\u003e\n\u003cspan\u003ePregnancy and lactation\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h5\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThere is no evidence of a malformation risk.\u003cspan\u003e \u003c\/span\u003eHowever, the documented human experience of use in early pregnancy is very limited.\u003cspan\u003e \u003c\/span\u003eThe medicinal product should therefore only be used after an appropriate benefit-risk assessment by the attending physician.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf magnesium is administered parenterally shortly before birth, the neonate should be monitored for signs of toxicity (neurological depression with respiratory depression, muscle weakness, loss of reflexes) during the first 24-48 hours of life.\u003cspan\u003e \u003c\/span\u003eThe administration of aminoglycoside antibiotics should be avoided during this period as there are indications of interactions.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDisorders of skeletal ossification in neonates have been reported with long-term parenteral use of magnesium to inhibit labor in high doses.\u003cspan\u003e \u003c\/span\u003eHowever, when used in the specified therapeutic dosage, there are no concerns in this regard.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch5 class=\"font-bold\"\u003e\n\u003cspan\u003ePatient Notes\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\n\u003c\/h5\u003e\n\u003cdiv class=\"prose mb-3.5 text-s last:mb-0\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eWarnings and Precautions\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePlease talk to your doctor or pharmacist before using the preparation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eParticular caution is required when using\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eFor severe renal excretion disorders.\u003cspan\u003e \u003c\/span\u003eA dose adjustment to the degree of the elimination disorder is necessary.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe following monitoring and precautionary measures should be taken during high-dose parenteral magnesium therapy:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eMonitoring of cardiovascular and respiratory function (respiratory rate not less than 16\/min),\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eExamination of the triggerability of the patellar tendon reflexes,\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDetermination of urine output (not less than 25 ml\/h),\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eProvision of ampoules of calcium gluconate, 10% as an antidote\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eGuaranteeing intensive medical measures if the antidote alone is not sufficient.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBecause of possible precipitation, the medicinal product should not be mixed with solutions containing calcium, phosphate, tetracycline or alcohol.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003echildren and young people\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eNo data is available.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eDriving and using machines:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eWhen used as intended, no special precautions are required.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e","brand":"Verla-Pharm Arzneimittel GmbH \u0026 Co. KG","offers":[{"title":"5 pcs","offer_id":54926101807481,"sku":"17638787","price":49.3,"currency_code":"GBP","in_stock":true},{"title":"50 pcs","offer_id":54926101840249,"sku":"17638793","price":295.35,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0903\/0792\/0249\/files\/treat-pre-eclampsia-eclampsia-pre-eclampsia-magnesium-verla-r-uk.jpg?v=1738733178","url":"https:\/\/ukdorf.co.uk\/products\/treat-pre-eclampsia-eclampsia-pre-eclampsia-magnesium-verla","provider":"UKDorf (ELIVERA) Buy online, Reviews Est. 1988 London, UK.","version":"1.0","type":"link"}