{"product_id":"pasconeural-procaine-hydrochloride","title":"PASCONEURAL, procaine hydrochloride","description":"\u003ch1\u003e\u003cspan data-mce-fragment=\"1\"\u003ePASCONEURAL, procaine hydrochloride 2% 5 ml ampoules\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eFor use within the framework of neural therapy application principles.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"a-h4 u-no-margin u-font-weight--bold\"\u003e\u003cspan\u003eactive PASCONEURAL, procaine hydrochloride ingredients\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"o-ProductAdditionalInformation u-clearfix\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e100 mg procaine hydrochloride\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"a-h4 u-no-margin u-font-weight--bold\"\u003e\u003cspan\u003ePASCONEURAL, procaine hydrochloride excipients\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"o-ProductAdditionalInformation u-clearfix\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003esodium chloride\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCitric acid monohydrate\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSodium hydroxide for pH adjustment\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ewater for injections\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eIndication\/ PASCONEURAL, procaine hydrochlorideApplication\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe preparation is a drug for local anesthetic (ester-type local anaesthetic)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt is used within the framework of neural therapy application principles.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003edosage\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAlways use the medicine exactly as directed.\u003cspan\u003e \u003c\/span\u003ePlease ask your doctor or pharmacist if you are not sure.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe drug is generally administered by a doctor.\u003cspan\u003e \u003c\/span\u003ePlease ask your doctor if you are unsure about the application.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn principle, only the smallest dose may be administered with which the desired sufficient nerve blockade is achieved.\u003cspan\u003e \u003c\/span\u003eThe dosage is to be made individually according to the characteristics of the individual case.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eUnless otherwise instructed by the doctor, the usual dose for each type of administration for adolescents over 15 years of age and adults of average height is:\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eskin wheals:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eup to 10 mg per wheal corresponding to 0.5 ml injection solution\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe maximum recommended dose for single use in tissues from which there is rapid absorption of drugs is 500 mg procaine (equivalent to 25 ml solution for injection).\u003cspan\u003e \u003c\/span\u003eWhen used on the head, neck and genitals, the maximum recommended dose is 200 mg procaine at one time (over a 2-hour period).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn patients with certain previous illnesses (vascular occlusions, vascular hardening and narrowing (arteriosclerosis) or nerve damage in diabetes), the dose should also be reduced by a third.\u003cspan\u003e \u003c\/span\u003eIn the case of impaired liver or kidney function, increased plasma levels can occur, especially with repeated use.\u003cspan\u003e \u003c\/span\u003eIn these cases a lower dose range is also recommended.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlease talk to your doctor if you have the impression that the effect is too strong or too weak.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eDuration of application:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIn principle, the duration of the application is not limited, but note the information under areas of application.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you use more than you should:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003ethe doctor treating you must be informed immediately.\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003ea.\u003cspan\u003e \u003c\/span\u003eSymptoms of an overdose\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eThe drug acts as a central nervous system stimulant in low damaging doses and has the opposite effect in high damaging dose ranges.\u003cspan\u003e \u003c\/span\u003eProcaine hydrochloride poisoning occurs in 2 phases:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThey become restless, complain of dizziness, acoustic and visual disturbances and tingling, especially in the tongue and lip area.\u003cspan\u003e \u003c\/span\u003eSpeech is slurred, chills and muscle spasms herald an impending whole-body seizure.\u003cspan\u003e \u003c\/span\u003eAs the poisoning of the central nervous system progresses, there is increasing dysfunction of the brainstem with the symptoms of restricted breathing and coma, leading to death.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eb.\u003cspan\u003e \u003c\/span\u003eEmergency measures and antidotes will be initiated immediately by the doctor treating you according to the signs of the disease.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you forgot the application:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eDo not apply a double dose to make up for a forgotten application.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you cancel the application:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe treatment can be stopped at any time.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eway\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe medicine is injected into the skin (intracutaneously).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt should only be sprayed by those with the knowledge to successfully complete the application.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBasically, with continuous use, only low-concentration solutions of procaine are used.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eRepeated use of this drug may result in reversible loss of efficacy due to tachyphylaxis (rapid development of tolerance to the drug).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe solution for injection is intended for single use only.\u003cspan\u003e \u003c\/span\u003eThe application must take place immediately after opening the container.\u003cspan\u003e \u003c\/span\u003eUnused residues are to be discarded.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eSide PASCONEURAL, procaine hydrochloride effects\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLike all medicines, this can cause side effects, although not everyone gets them.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ePossible side effects:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIf you are affected by any of the side effects listed below, stop using the product and contact your doctor as soon as possible.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAdverse effects of procaine affecting the whole body primarily affect the central nervous and cardiovascular systems.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAt plasma concentrations such as are generally reached with regular use, the blood pressure is usually only slightly influenced by the effect that promotes heart strength and heart rate.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eProcaine can cause changes in the heart's pacing pattern, which show up on the EKG (as a flattened T wave or shortened ST segment).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eA drop in blood pressure can be the first sign of a relative overdose in the sense of a heart-damaging effect.\u003cspan\u003e \u003c\/span\u003eDisorders of the central nervous system such as abnormal sensations around the mouth, restlessness, disturbances of consciousness or a seizure can be triggered.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAllergic reactions in the form of hives, swelling of the tissue due to water retention, spasms of the airways or shortness of breath, and circulatory reactions have been described.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLocal allergies and allergy-like reactions in the form of skin inflammation with skin reddening, itching and even blistering can occur on contact with ester local anesthetics such as this medicine.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn addition, when used under the skin (subcutaneously) and in the muscle (intramuscularly), local reactions such as swelling, reddening of the skin and bruising can occur.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you get any side effects, talk to your doctor or pharmacist.\u003cspan\u003e \u003c\/span\u003eThis also applies to side effects that are not specified.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003einteractions\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eUse with other medicines:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePlease inform your doctor or pharmacist if you are taking\/using or have recently taken\/used other medicines, even if they are non-prescription medicines.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe following interactions of procaine with other medicines are known:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eProlongation of the effect of certain skeletal muscle relaxants (non-depolarizing muscle relaxants)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eEnhancement of the effect of physostigmine (agent for stimulating part of the autonomic nervous system)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReduction in the effectiveness of certain antibiotics (sulfonamides).\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eProcaine should not be used together with certain drugs that stimulate part of the autonomic nervous system (cholinesterase inhibitors).\u003cspan\u003e \u003c\/span\u003eAmong other things, the influence on procaine degradation leads to an increase in the toxicity of procaine.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBy adding small amounts of atropine, it is possible to prolong the pain-relieving effect.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePhysostigmine (see above) in low doses can have a preventive effect against the toxic effects of procaine.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eMain chemical intolerances:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eProcaine should not be mixed with other drugs because a change in pH or electrolyte concentration can cause the active ingredient to precipitate.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eUse with food and drink:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eNo mutual interference is to be expected, as this is an injection solution, ie it is used bypassing the gastrointestinal tract.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003ePASCONEURAL, procaine hydrochloride Contraindications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eThe medicine must not be used:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eif you are allergic (hypersensitive) to procaine, other local ester-type anaesthetics, sulphonamides (certain group of antibiotics), benzoic acid (parabens) or any of the other ingredients of this medicine\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eif there is a known deficiency of a specific endogenous substance (pseudocholinesterase) resulting in a significantly slower breakdown of procaine\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003efor injection into arteries, in the vicinity of the outer covering skin of the central nervous system (epidural) or in the spinal canal (spinal).\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003epregnancy PASCONEURAL, procaine hydrochloride and breast feeding period\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003epregnancy\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eOnly allow the medicine to be used during pregnancy if your doctor considers it absolutely necessary.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eBreastfeeding:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eProcaine hydrochloride passes into breast milk.\u003cspan\u003e \u003c\/span\u003eHowever, with short-term use, discontinuation of breastfeeding will not be necessary.\u003cspan\u003e \u003c\/span\u003eIf repeated treatment or treatment with higher doses is necessary, you should stop breast-feeding.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003ePatient information\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eWarnings and Precautions:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eParticular caution is required when using it if you have a\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ecertain form of muscle weakness (myasthenia gravis)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDisturbance of the cardiac conduction system\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003esuffer from cardiac insufficiency or\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ethe injection is to be made in an inflamed area.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBefore use, the doctor using the drug will always ensure that the circulation is properly filled, monitor the circulation carefully and have all measures available for ventilation, therapy for seizures and resuscitation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eYou will also need to tell the doctor if you have had an allergic reaction to other medicines that are chemically related to procaine, as you may also have an allergic reaction to procaine (paragroup allergy).\u003cspan\u003e \u003c\/span\u003eThis can e.g.\u003cspan\u003e \u003c\/span\u003eB. be sulfonamides (a group of antibiotics), oral antidiabetics (medicines for diabetes), certain dyes, X-ray film developers or other local anesthetics.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you are only able to break down procaine extremely slowly because a certain body substance is not as active (pseudocholinesterase deficiency), procaine side effects may be more likely to occur.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWhen used in the neck and head area, there is a higher degree of danger because the risk of symptoms of poisoning in the central nervous system is increased.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eTo avoid side effects, the following points should be observed:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIn certain cases, put on an additional drip before use.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eChoose dosage as low as possible.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAs a rule, do not use a vasoconstrictor additive.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCarefully aspirate in two planes (rotate the cannula) before injecting.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCaution when injecting into infected areas (due to increased uptake with decreased efficacy).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInject slowly.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCheck blood pressure, pulse and pupil size.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt should be noted that during treatment with anticoagulants (anticoagulants such as heparin), non-steroidal anti-inflammatory drugs or plasma substitutes, not only accidental vascular injury in the context of pain treatment can lead to serious bleeding, but that an increased tendency to bleed in general must be expected .\u003cspan\u003e \u003c\/span\u003eTherefore, have appropriate laboratory tests carried out before use.\u003cspan\u003e \u003c\/span\u003eIf necessary, the anticoagulant treatment should be discontinued in good time.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eUse with simultaneous preventive therapy to avoid thrombosis with low molecular weight heparin should only be carried out with particular caution.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eChildren:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThere is no application experience from which general dosage recommendations can be derived for use in children and adolescents under the age of 15.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eElderly people:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eDose adjustment is recommended in the elderly according to their general condition.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eDriving and using machines:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLet your doctor decide on a case-by-case basis whether you can actively participate in road traffic, operate machines or carry out work without a secure footing.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Pascoe pharmaceutical preparations GmbH","offers":[{"title":"5 pc","offer_id":54927186723193,"sku":"11170024","price":69.78,"currency_code":"GBP","in_stock":false},{"title":"50 pc","offer_id":54927186755961,"sku":"11170030","price":248.85,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0903\/0792\/0249\/files\/pasconeural-procaine-hydrochloride-uk-1.jpg?v=1738761758","url":"https:\/\/ukdorf.co.uk\/products\/pasconeural-procaine-hydrochloride","provider":"UKDorf (ELIVERA) Buy online, Reviews Est. 1988 London, UK.","version":"1.0","type":"link"}