{"product_id":"pasconeural-local-anesthesia-procaine-hydrochloride","title":"PASCONEURAL, local anesthesia, procaine hydrochloride","description":"\u003ch1 data-mce-fragment=\"1\" itemprop=\"name\" content=\"PASCONEURAL-Injektopas-2-2-ml-Inj-Loesung-Amp\"\u003e\u003cspan data-mce-fragment=\"1\"\u003elocal anesthesia, PASCONEURAL Injektopas 2% 2 ml Inj. Solution Ampoules, procaine hydrochloride\u003c\/span\u003e\u003c\/h1\u003e\n\u003ch3 class=\"a-h4 u-no-margin u-font-weight--bold\"\u003e\u003cspan\u003eActive for local anesthesia ingredients\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"o-ProductAdditionalInformation u-clearfix\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e40 mg procaine hydrochloride\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"a-h4 u-no-margin u-font-weight--bold\"\u003e\u003cspan\u003eAuxiliary for local anesthesia materials\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"o-ProductAdditionalInformation u-clearfix\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eSodium chloride\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCitric acid monohydrate\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSodium hydroxide for pH adjustment\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWater for injections\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eIndication \/ for local anesthesia, procaine hydrochloride application\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe preparation is a medicine for local anesthesia (local anesthetic of the ester type)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt is used in the context of neural therapeutic application principles.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003edosage\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAlways use the medicine exactly as directed.\u003cspan\u003e \u003c\/span\u003ePlease ask your doctor or pharmacist if you are not sure.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe medicine is generally administered by a doctor.\u003cspan\u003e \u003c\/span\u003ePlease ask your doctor if you are not sure how to use it.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe basic rule is that only the smallest dose may be administered with which the desired adequate nerve block is achieved.\u003cspan\u003e \u003c\/span\u003eThe dosage is to be carried out individually according to the particularities of the individual case.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eUnless otherwise used by the doctor:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAdults and adolescents from 15 years of age with an average height:\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eSkin wheals:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eUp to 10 mg per wheal, corresponding to 0.5 ml solution for injection.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe recommended maximum dose for single use in tissues from which medicinal substances are rapidly absorbed is 500 mg procaine (corresponding to 25 ml injection solution).\u003cspan\u003e \u003c\/span\u003eFor use in the head, neck and genital area, the recommended maximum single dose is 200 mg procaine (within 2 hours).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn patients with certain pre-existing conditions (vascular occlusions, hardening and narrowing of the vessels (arteriosclerosis) or nerve damage due to diabetes) the dose should also be reduced by a third.\u003cspan\u003e \u003c\/span\u003eWith impaired liver or kidney function, increased plasma levels can occur, especially with repeated use.\u003cspan\u003e \u003c\/span\u003eIn these cases, a lower dose range is also recommended.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlease talk to your doctor if you have the impression that the effect is too strong or too weak.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eDuration of application:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIn principle, there is no limit to the duration of use, but please note the information given under areas of application.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you use more than you should,\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003ethe attending physician must be informed immediately.\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003ea.\u003cspan\u003e \u003c\/span\u003eSymptoms of overdose\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIn low damaging doses, the drug acts as a stimulant on the central nervous system; in high damaging dose ranges, it works in the opposite direction.\u003cspan\u003e \u003c\/span\u003eProcaine hydrochloride poisoning has two phases:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThey become restless, complain of dizziness, acoustic and visual disturbances and tingling, especially in the tongue and lip area.\u003cspan\u003e \u003c\/span\u003eThe language is slurred, chills and muscle twitching are harbingers of an impending seizure affecting the whole body.\u003cspan\u003e \u003c\/span\u003eAs the poisoning of the central nervous system progresses, there is an increasing dysfunction of the brain stem with symptoms of impaired breathing and coma up to and including death.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eb.\u003cspan\u003e \u003c\/span\u003eEmergency measures and antidotes are set by the attending physician accordingly\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ethe symptoms are initiated immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you forget to use:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eDo not use a double dose to make up for a forgotten dose.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you cancel the application:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe treatment can be canceled at any time.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eway\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe medicine is injected into the skin (intracutaneously).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt should only be sprayed by people with the appropriate knowledge to successfully carry out the respective application.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAs a general rule, only low-concentration solutions of procaine are used for continuous use.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eRepeated use of this drug can lead to reversible loss of effectiveness due to tachyphylaxis (rapid development of tolerance to the drug).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe solution for injection is only intended for single withdrawal.\u003cspan\u003e \u003c\/span\u003eThe application must take place immediately after opening the container.\u003cspan\u003e \u003c\/span\u003eUnused leftovers are to be discarded.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eSide procaine hydrochloride effects\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLike all medicines, this can cause side effects, although not everybody gets them.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe frequency of side effects is based on the following categories:\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ePossible side effects:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIf you experience any of the side effects listed below, stop using the medicine and contact your doctor as soon as possible.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAdverse effects of procaine affecting the whole body primarily affect the central nervous and cardiovascular systems.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAt plasma concentrations, as they are generally achieved with regular use, the blood pressure is usually only slightly influenced by the effect that promotes the strength and rate of the heart.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eProcaine can trigger changes in the spread of excitation in the heart, which show up in the ECG (as a flattened T wave or shortened ST segment).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eA drop in blood pressure can be the first sign of a relative overdose in terms of heart-damaging effects.\u003cspan\u003e \u003c\/span\u003eAs central nervous disorders, abnormal sensations around the mouth area, restlessness, impaired consciousness or a seizure can be triggered.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAllergic reactions in the form of hives, swelling of the tissue due to water retention, cramping of the airways or shortness of breath and circulatory reactions have been described.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLocal allergies and allergy-like reactions in the form of skin inflammation with reddening of the skin, itching and even blistering can occur on contact with ester local anesthetics like this one.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn addition, local reactions when used under the skin (subcutaneous) and in the muscles (intramuscular) may include swelling, reddening of the skin and bruising.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you get any side effects, talk to your doctor or pharmacist.\u003cspan\u003e \u003c\/span\u003eThis also applies to side effects that are not specified.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eInteractions\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eUse with other medicinal products:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePlease inform your doctor or pharmacist if you are taking \/ using or have recently taken \/ used any other medicines, including medicines obtained without a prescription.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe following interactions of procaine with other drugs are known:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eProlongation of the effect of certain means to relax the skeletal muscles (non-depolarizing muscle relaxants)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eEnhancement of the effect by physostigmine (agent for stimulating part of the autonomic nervous system)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDecrease in the effectiveness of certain antibiotics (sulfonamides).\u003cspan\u003e \u003c\/span\u003eProcaine should not be used together with certain agents to stimulate part of the autonomic nervous system (cholinesterase inhibitors).\u003cspan\u003e \u003c\/span\u003eAmong other things, the influence on procaine breakdown leads to an increase in the toxicity of procaine.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBy adding small amounts of atropine, the pain-eliminating effect can be prolonged.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePhysostigmine in low doses can have a preventive effect against the toxic effects of procaine.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eMost important chemical incompatibilities:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eProcaine should not be mixed with other medicinal products, as a change in the pH value or the electrolyte concentration can lead to the precipitation of the active ingredient.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eUse with food and drink:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eNo mutual interference is to be expected, since it is an injection solution, ie it is used bypassing the gastrointestinal tract.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eContraindications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eThe drug must not be used:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eif you are allergic (hypersensitive) to procaine, other local anesthetics of the ester type or any of the other ingredients\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ein the case of a known deficiency of a certain endogenous substance (pseudocholinesterase) with the consequence of a considerably slower breakdown of procaine\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFor injection into arteries, in the vicinity of the outer covering of the central nervous system (epidural) or in the vertebral canal (spinal).\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003epregnancy for local anesthesia, procaine hydrochloride and breast feeding period\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003ePregnancy:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eOnly use the medicine during pregnancy if your doctor thinks it is absolutely necessary.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eBreastfeeding:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eProcaine hydrochloride passes into breast milk.\u003cspan\u003e \u003c\/span\u003eHowever, with short-term use, it will not be necessary to interrupt breastfeeding.\u003cspan\u003e \u003c\/span\u003eIf repeated treatment or treatment with higher doses is necessary, breastfeeding should be discontinued.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003ePatient, local anesthesia, procaine hydrochloride information\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eWarnings and Precautions:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eif you are in a\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ecertain form of muscle weakness (myasthenia gravis)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDisturbance of the cardiac conduction system\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSuffer from heart failure or\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ethe injection is to be made in an inflamed area.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBefore use, the doctor who uses it will always ensure that the circulation is properly replenished, carefully monitor the circulation and have all ventilation, seizure therapy and resuscitation measures available.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe doctor must also find out from you whether you have had an allergic reaction to other drugs that are chemically related to procaine, as this can also lead to an allergic reaction to procaine (para group allergy).\u003cspan\u003e \u003c\/span\u003eThis can e.g.\u003cspan\u003e \u003c\/span\u003eB. be sulfonamides (certain group of antibiotics), oral antidiabetic drugs (agents for diabetes), certain dyes, X-ray film developer or other means of local anesthesia.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you can only break down procaine extremely slowly because a certain body substance is not as active (pseudocholinesterase deficiency), side effects from procaine are more likely to occur.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWhen used in the neck and head area, there is a higher degree of danger because the risk of symptoms of poisoning in the central nervous system is increased.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eTo avoid side effects, the following points should be observed:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIn certain cases, put on a drip before use.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eChoose the dosage as low as possible.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAs a rule, do not use a vasoconstrictor additive.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBefore the injection, carefully aspirate in two planes (turn the cannula).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCaution when injecting into infected areas (due to increased absorption with reduced effectiveness).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInject slowly.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCheck blood pressure, pulse and pupil size.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt should be noted that treatment with anti-coagulants (anticoagulants such as heparin), non-steroidal anti-inflammatory drugs or plasma substitutes can lead to serious bleeding not only inadvertent vascular injury as part of pain treatment, but also in general with an increased tendency to bleed .\u003cspan\u003e \u003c\/span\u003eTherefore, have appropriate laboratory tests carried out before use.\u003cspan\u003e \u003c\/span\u003eIf necessary, the anticoagulant treatment should be discontinued early enough.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eUse with simultaneous preventive therapy to avoid thrombosis with low molecular weight heparin should only be carried out with particular caution.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eChildren:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eFor use in children and adolescents under 15 years of age, there is no experience from which general dosage recommendations can be derived.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eElderly people:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIn the elderly, it is recommended that the dose be adjusted according to their general condition.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eDriving and using machines:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLet your doctor decide on a case-by-case basis whether you can actively participate in road traffic, use machines or carry out work without a secure footing.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Pascoe pharmaceutical preparations GmbH","offers":[{"title":"10 pc","offer_id":54927196815737,"sku":"11170001","price":30.98,"currency_code":"GBP","in_stock":false},{"title":"100 pc","offer_id":54927196848505,"sku":"11170018","price":368.93,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0903\/0792\/0249\/files\/pasconeural-local-anesthesia-procaine-hydrochloride-uk-1.jpg?v=1738761836","url":"https:\/\/ukdorf.co.uk\/products\/pasconeural-local-anesthesia-procaine-hydrochloride","provider":"UKDorf (ELIVERA) Buy online, Reviews Est. 1988 London, UK.","version":"1.0","type":"link"}