{"product_id":"paraesthesia-diabetes-mellitusdiabetic-polyneuropathy-biomo-lipon-600-mg-ampoules","title":"Paraesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon 600 mg ampoules","description":"\u003ch1\u003eParaesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon 600 mg ampoules\u003c\/h1\u003e\n\u003cp\u003e\u003cspan\u003eBiomo-lipon® 600 mg concentrate for infusion solution\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eActive ingredient: a-lipoic acid, ethylene bis(azane) salt\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eAreas of application: Discomfort in diabetic polyneuropathy.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"my-4\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"wysiwyg\"\u003e\n\u003ch2\u003e\u003cspan\u003e\u003cstrong\u003e\u003cspan\u003eParaesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO LIPON 600mg ampoules\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe infusion set contains a high concentration of the natural enzyme component alpha-lipoic acid.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe alpha lipoic acid used in biomo-lipon 600 mg is of the highest quality.\u003cspan\u003e \u003c\/span\u003eIt can be easily absorbed by the human body and develops an intensive effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eParaesthesia in diabetic polyneuropathy caused by diabetes mellitus.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"mt-8\"\u003e\n\u003cdiv class=\"bg-grey-lighter text-xs rounded p-3 mt-2\"\u003e\n\u003cp\u003e\u003cspan\u003eFor medicines: Read the leaflet on the risks and side effects and ask your doctor or pharmacist.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"a-h4 u-no-margin u-font-weight--bold\"\u003e\u003cspan\u003eactive Paraesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon ingredients\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"o-ProductAdditionalInformation u-clearfix\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e687.38 mg α-lipoic acid, ethylenediamine salt (2:1)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"a-h4 u-no-margin u-font-weight--bold\"\u003e\u003cspan\u003eexcipients\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"o-ProductAdditionalInformation u-clearfix\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ewater for injections\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eethylenediamine\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cem\u003eParaesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon indication\u003c\/em\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAlpha-lipoic acid is a substance formed in higher organisms in the body's own metabolism, which influences certain metabolic processes in the body.\u003cspan\u003e \u003c\/span\u003eIn addition, alpha-lipoic acid has antioxidative properties that protect nerve cells from reactive degradation products.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe drug is used in\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eParaesthesia with diabetic nerve damage (polyneuropathy)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan style=\"text-decoration: underline;\"\u003edosage Paraesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAlways use the medicine exactly as directed.\u003cspan\u003e \u003c\/span\u003ePlease check with your doctor or pharmacist if you are not sure.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eUnless otherwise prescribed by the doctor, is the usual dose\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIn the case of severe abnormal sensations associated with diabetic polyneuropathy, a once-daily infusion of 1 ampoule (equivalent to 600 mg alpha-lipoic acid) in isotonic saline solution is recommended for adults.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAfter the contents have been mixed with 250 ml isotonic saline solution, the intravenous administration should take place over at least 30 minutes as a short infusion.\u003cspan\u003e \u003c\/span\u003eDue to the photosensitivity of the active ingredient, the short infusion should only be prepared shortly before use.\u003cspan\u003e \u003c\/span\u003eThe infusion solution should be protected from light with aluminum foil.\u003cspan\u003e \u003c\/span\u003eProtected from light, the infusion solution can be stored for approx. 6 hours.\u003cspan\u003e \u003c\/span\u003eIt must be ensured that the minimum infusion time of 30 minutes is observed.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe drug is used as an infusion with isotonic saline solution over a period of 2-4 weeks in the initial phase of treatment.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAs a further therapy, 300 - 600 mg alpha-lipoic acid should be taken daily in the form of capsules, tablets or coated tablets.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlease talk to your doctor or pharmacist if you have the impression that the effect is too strong or too weak.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eIf you use more than you should\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eOverdose may cause nausea, vomiting and headaches.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIn individual cases, severe, e.g.\u003cspan\u003e \u003c\/span\u003eT. life-threatening symptoms of poisoning observed (such as generalized seizures, derailment of the acid-base balance with lactic acidosis, severe blood clotting disorders).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eTherefore, if a significant overdose is suspected, immediate hospital admission and the initiation of measures according to the general treatment principles for cases of poisoning are required.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIf you have any further questions on the use of the medicine, ask your doctor or pharmacist.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eway Paraesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe preparation may only be administered as an infusion in isotonic saline solution\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan style=\"text-decoration: underline;\"\u003eside Paraesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon effects\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLike all medicines, the preparation can have side effects, although not everyone gets them.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe evaluation of side effects is based on the following frequency information:\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003every common: more than 1 in 10 people treated\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCommon: less than 1 in 10 but more than 1 in 100 people treated\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003euncommon: less than 1 in 100 but more than 1 in 1000 people treated\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003erare: less than 1 in 1000 but more than 1 in 10,000 people treated\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003every rare: less than 1 in 10,000 people treated, including isolated cases\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAfter rapid intravenous injection, pressure in the head and shortness of breath often occur, which resolve spontaneously.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eTaste disturbances occur very rarely.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInjection site reactions have been reported very rarely.\u003cspan\u003e \u003c\/span\u003eAllergic reactions of the skin with hives (urticaria), itching, eczema and skin rash as well as hypersensitivity of the whole body up to shock can occur.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eVery rarely, after intravenous administration of alpha-lipoic acid, seizures, double vision, spontaneous bleeding in small patches in the skin (purpura) and functional disorders of the blood platelets and thus blood clotting (thrombopathies) have been observed.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eVery rarely, due to improved glucose utilization, blood sugar levels may drop.\u003cspan\u003e \u003c\/span\u003eSymptoms like hypoglycaemia with dizziness, sweating, headaches and visual disturbances were described.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003ecountermeasures\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIf you notice the side effects mentioned above, the drug should not be used again.\u003cspan\u003e \u003c\/span\u003eNotify your doctor so he can decide on the severity and any further action that may be needed.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAt the first sign of a hypersensitivity reaction, the drug should be discontinued and a doctor contacted immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIf you get any side effects, talk to your doctor or pharmacist.\u003cspan\u003e \u003c\/span\u003eThis also applies to side effects that are not specified.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan\u003eParaesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon interactions\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eWhen used with other medicines\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePlease inform your doctor or pharmacist if you are taking\/using or have recently taken\/used other medicines, even if they are non-prescription medicines.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIt cannot be ruled out that concomitant use will lead to a loss of effectiveness of cisplatin (a cancer drug).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe blood sugar-lowering effect of insulin or oral antidiabetics can be increased.\u003cspan\u003e \u003c\/span\u003eClose blood sugar monitoring is therefore indicated, particularly in the early stages of therapy.\u003cspan\u003e \u003c\/span\u003eIn individual cases, it may be necessary to reduce the insulin dose or the dose of the oral antidiabetic in accordance with the instructions of the attending physician in order to avoid symptoms of hypoglycaemia.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eWhen used with food and drink\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThe regular consumption of alcohol represents a significant risk factor for the development and progression of neuropathic diseases and can thus also impair the success of a treatment.\u003cspan\u003e \u003c\/span\u003eTherefore, patients with diabetic polyneuropathy are generally recommended to avoid the consumption of alcohol as far as possible.\u003cspan\u003e \u003c\/span\u003eThis also applies to therapy-free intervals.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eContraindications\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eThe medicine must not be used\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eif you are allergic (hypersensitive) to alpha-lipoic acid or any of the other ingredients\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003epregnancy and breast feeding period\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eIt is in accordance with the general principles of pharmacotherapy to use drugs during pregnancy and breastfeeding only after carefully weighing the benefits and risks.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePregnant and breastfeeding women should only undergo treatment with alpha-lipoic acid after careful recommendation and monitoring by their doctor, as there is no experience with this group of patients to date.\u003cspan\u003e \u003c\/span\u003eSpecial studies on animals have not produced any indications of fertility disorders or teratogenic effects.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eNothing is known about a possible transfer of alpha-lipoic acid into breast milk.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan style=\"text-decoration: underline;\"\u003epatient Paraesthesia, diabetes mellitus, Diabetic polyneuropathy, BIOMO-lipon notes\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eParticular caution in use is required\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eAllergic reactions (hypersensitivity reactions up to life-threatening shock (sudden circulatory failure) have been observed in connection with the use of alpha-lipoic acid as an injection or infusion solution. For this reason, your treating doctor will monitor you during use for the occurrence of early symptoms (e.g. itching , nausea, malaise, etc.) If these occur, the therapy must be stopped immediately and further therapy measures may be necessary.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAlpha-lipoic acid reacts in vitro with metal ion complexes (e.g. with cisplatin), alpha-lipoic acid forms poorly soluble complex compounds with sugar molecules (e.g. levulose solution).\u003cspan\u003e \u003c\/span\u003eThe medicinal product is incompatible with glucose solution, Ringer's solution and with solutions known to react with SH groups or disulfide bridges.\u003cspan\u003e \u003c\/span\u003eOnly isotonic saline solution should be used as the carrier solution for the infusion application.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003echildren\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eChildren and adolescents should be excluded from treatment as there is no clinical experience in this age group.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eDriving and using machines\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThere are no special precautions required.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"biomo pharma GmbH","offers":[{"title":"5 pcs","offer_id":54926224556409,"sku":"06897617","price":78.39,"currency_code":"GBP","in_stock":true},{"title":"10 pcs","offer_id":54926224589177,"sku":"06897623","price":142.2,"currency_code":"GBP","in_stock":true},{"title":"20 pcs","offer_id":54926224621945,"sku":"06897646","price":282.9,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0903\/0792\/0249\/files\/paraesthesia-diabetes-mellitus-diabetic-polyneuropathy-biomo-lipon-600-mg-ampoules-uk-1.jpg?v=1738737397","url":"https:\/\/ukdorf.co.uk\/products\/paraesthesia-diabetes-mellitusdiabetic-polyneuropathy-biomo-lipon-600-mg-ampoules","provider":"UKDorf (ELIVERA) Buy online, Reviews Est. 1988 London, UK.","version":"1.0","type":"link"}